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Patel Hirenkumar, R.
- Current Scenario in Coronary Stenting–A Review
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1 Department of Pharmacy, JJT University, Vidyanagari, Churu Jhunjhunu Road, Chudela, District-Jhunjhunu–333001, Rajasthan, IN
1 Department of Pharmacy, JJT University, Vidyanagari, Churu Jhunjhunu Road, Chudela, District-Jhunjhunu–333001, Rajasthan, IN
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Research Journal of Pharmacology and Pharmacodynamics, Vol 5, No 1 (2013), Pagination: 12-18Abstract
In this review article many research and review article on coronary stent has been reviewed thoroughly and prepared a review on the same basis. Percutaneous Coronary Interventions refers to both non-stenting procedures and stent interventions. Various types of stents are available in both Bare Metal Stent (BMS) as well as Drug Eluting Stent (DES). Various safety and efficacy studies have been performed to compare BMS and DES with variety of variables. Many studies favor BMS as a good option at low cost. However in the support of DES, many studies results show it's not inferior in term of safety than BMS. Even there are data available for comparative studies between BMS and DES for effectiveness by assessing Major Adverse Cardiac Event (MACE). Studies prove non inferiority of DES compared to BMS. Cost of DES is higher than BMS, in general, but Pharmacoeconomical Studies indicate that DES has greater ratio of effectiveness than cost.Keywords
PCI, Stent, BMS, DES, MACEReferences
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- Antihypertensive Drugs prescribed in West Indian Territories
Abstract Views :267 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmacy, JJT University, Vidyanagari, Churu Jhunjhunu Road, Chudela, District-Jhunjhunu –333001, Rajasthan, IN
1 Department of Pharmacy, JJT University, Vidyanagari, Churu Jhunjhunu Road, Chudela, District-Jhunjhunu –333001, Rajasthan, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 5, No 1 (2013), Pagination: 75-78Abstract
Management of hypertension in patients provides a significant challenge for healthcare professionals. It was convincingly demonstrated that lowering of blood pressure below what is recommended for patients with essential hypertension. The present study was done to find prescription trend in Indian cardiology and nephrology practice and its adherence to therapeutic guidelines. For present study, 120 patients having blood pressure greater or equal to 140/90 mm Hg and fulfilling inclusion-exclusion criteria were enrolled and data of Serum Creatinine and Blood Pressure were recorded at 0 week, 4 week, 8 week and 12 week. In treatment strategy, Goal of blood pressure is to achieve BP up to <130/80 mmHg for all patients. There is still controversy about effectiveness of antihypertensive drugs in CKD. In view of JNC VII guideline, ACE inhibitors should be used as first line treatment. It may surprising in this study that ACE inhibitors or Angiotensin receptor blockers were used only in 50% of the patients, whereas Diuretics were in 87% and Calcium channel blockers were prescribed in 73% patients. It was found that physicians hesitate to prescribe ACE inhibitors as first line treatment due to serious side effects such as brassy cough and hyperkalemia. It was concluded that there is still potential to increase the prescription frequency of ACE inhibitors and AT1 blockers. Management of Hypertension is more difficult in renal patients and requires multi drug therapy, which is further influenced adversely by diabetic condition.Keywords
Hypertension, ACE Inhibitors, BP, CKD, AT1 BlockersReferences
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